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发布旉™—´åQ?023/11/6 9:45:37 </div> <div class="info"> <p style="text-align: justify; text-indent: 2em;"><span style="text-indent: 28px; font-family: 宋体;">˜q‘日在门诊中åQŒæ£€æŸ¥å®¤æ¥äº†ä¸€ä½?岁小男孩åQŒå®¶é•¿è¡¨½Cºå­©å­åœ¨òq¼å„¿å›­ä½“‹‚€æ—¶å‘现左çœÆD§†åŠ›å¾ˆå·®ï¼Œ˜q™å¯æ€¥åä»–们一家了。经˜q‡ä¸€¾pÕdˆ—详细的检查,åŒÈ”Ÿ¼‹®è¯Šž®ç”·å­©æ‚£æœ‰å®¶æ—æ€§æ¸—出性玻璃体视网膜病å?/span><span style="text-indent: 28px; font-family: 宋体;">(familial exudative vitreoretinopathy</span><span style="text-indent: 28px; font-family: 宋体;">,½Ž€¿U?/span><span style="text-indent: 28px; font-family: 宋体;">FEVR)ã€?/span></p><p style="text-align: justify; text-indent: 2em;"><span style="text-indent: 28px; font-family: 宋体;">˜q™æ˜¯ä»€ä¹ˆç—…åQŸäؓ什么会患上˜q™ç§ç—…å‘¢åQŸè¿™¿Uç—…能治好吗åQŸæ€Žä¹ˆé¢„防˜q™ç§ç—…å‘¢åQŸå¸¦ç€˜q™äº›é—®é¢˜åQŒä¸‹é¢æˆ‘们就介绍一下F</span><span style="text-indent: 28px; font-family: 宋体;">EVR</span><span style="text-indent: 28px; font-family: 宋体;">˜q™ç§çœ¼ç§‘ç–„¡—…ã€?/span></p><p style="background: rgb(255, 255, 255); text-indent: 2em;"><span style=";font-family:宋体;font-size:14px">FEVR</span><span style=";font-family:宋体;font-size:14px"><span style="font-family:宋体">是什么眼¿U‘疾病呢åQ?/span></span></p><p style="background: rgb(255, 255, 255); text-indent: 2em;"><span style="font-family: 宋体;">FEVR是儿童期主要的致盲性眼病之一</span><span style="font-family: 宋体;">åQ?/span><span style="font-family: 宋体;">眼底主要表现ä¸ø™§†¾|‘膜血½Ž¡å‘育异常或不发è‚ÔŒ¼Œ</span><span style="font-family: 宋体;">引è“v</span><span style="font-family: 宋体;">周边视网膜无灌注和新生血½Ž¡ç”Ÿæˆï¼Œ</span><span style="font-family: 宋体;">重者可致视¾|‘膜è„Þq¦»åQŒæˆ–çŽÈ’ƒä½“积血、新生血½Ž¡æ€§é’光眼而失明ã€?/span><span style="font-family: 宋体;">FEVR</span><span style="font-family: 宋体;">在全òq´é¾„</span><span style="font-family: 宋体;">ŒD?/span><span style="font-family: 宋体;">均有病变发展</span><span style="font-family: 宋体;">ã€?/span><span style="font-family: 宋体;">威胁视力的可èƒ?/span><span style="font-family: 宋体;">åQ?/span><span style="font-family: 宋体;">ä½?/span><span style="font-family: 宋体;">å©´å¹¼å„?/span><span style="font-family: 宋体;">期发展更ä¸ø™¿…é€?/span><span style="font-family: 宋体;">åQŒæˆòq´æ‚£è€…病情相对稳定。本病多为双眼发病,临床表现å¸æ€¸å¯¹ç§°åQŒçœ¼åº•è¡¨çŽîC¹Ÿå¤šç§å¤šæ ·åQŒå¯¹äºŽåŒä¸€æ‚£è€…,可能一只眼已发生完全性视¾|‘膜è„Þq¦»åQŒå¦ä¸€åªçœ¼æ— æ˜Žæ˜¾äÍ床症状ã€?/span></p><p style="background: rgb(255, 255, 255); text-indent: 2em;"><span style=";font-family:宋体;font-size:14px">ä¸ÞZ»€ä¹ˆä¼šæ‚£ä¸Š˜q™ç§ç—…å‘¢åQ?/span></p><p style="text-indent: 28px;background: rgb(255, 255, 255)"><span style="font-family: 宋体;font-size: 14px">F</span><span style="font-family: 宋体;font-size: 14px">EVR是一¿U?/span><span style="font-family: 宋体;font-size: 14px">先天性遗传疾病,¾U?/span><span style="font-family: 宋体;font-size: 14px">50åQ…的患者有é˜Ïx€§çš„家族å?/span><span style="font-family: 宋体;font-size: 14px">ã€?/span><span style="font-family: 宋体;font-size: 14px">FEVR</span><span style="font-family: 宋体;font-size: 14px">早期</span><span style="font-family: 宋体;font-size: 14px">可以没有ä»ÖM½•ä¸´åºŠè¡¨çŽ°åQ?/span><span style="font-family: 宋体;font-size: 14px">发现更äؓ困难</span><span style="font-family: 宋体;font-size: 14px">ã€?/span><span style="font-family: 宋体;font-size: 14px">以往多认ä¸?/span><span style="font-family: 宋体;font-size: 14px">FEVR是一¿Uç½•è§ç—…, 但近</span><span style="font-family: 宋体;font-size: 14px">òq?/span><span style="font-family: 宋体;font-size: 14px"><span style="font-family:宋体">来在新生儿眼底筛查中发现</span>FEVR 的发病率可达1</span><span style="font-family: 宋体;font-size: 14px">.</span><span style="font-family: 宋体;font-size: 14px">19åQ?/span><span style="font-family: 宋体;font-size: 14px">åQŒåº”当得到重è§?/span><span style="font-family: 宋体;font-size: 14px">ã€?/span><span style="font-family: 宋体;"> </span></p><p style="text-indent: 28px;background: rgb(255, 255, 255)"><span style="font-family: 宋体;">FEVR</span><span style="font-family: 宋体;">能治好吗åQ?/span></p><p style="text-indent: 28px;background: rgb(255, 255, 255)"><span style="font-family: 宋体;font-size: 14px">FEVR的一个重要特点就是“终íw«å…·æœ‰æ´»åŠ¨æ€§â€ï¼Œç—…情ž®±åƒâ€œæ´»ç«å±±â€?</span><span style="font-family: 宋体;font-size: 14px">可终生不æ–?/span><span style="font-family: 宋体;font-size: 14px">˜q›å±•åQ?/span><span style="font-family: 宋体;font-size: 14px">表现为静止期和进展期åQŒå¯é™æ­¢æ•°å¹´åŽåˆå¼€å§‹æ´»åŠ¨ï¼Œéœ€è¦ç»ˆíw«éšè®?/span><span style="font-family: 宋体;font-size: 14px">监测</span><span style="font-family: 宋体;font-size: 14px">ã€?/span></p><p style="text-indent: 28px;background: rgb(255, 255, 255)"><span style="font-family: 宋体;font-size: 14px">目前</span><span style="font-family: 宋体;font-size: 14px">FEVR的诊断主要通过å…?/span><span style="font-family: 宋体;font-size: 14px">临床特点、眼底荧光素造媄</span><span style="font-family: 宋体;font-size: 14px">(</span><span style="font-family: 宋体;font-size: 14px">F</span><span style="font-family: 宋体;font-size: 14px">FA)</span><span style="font-family: 宋体;font-size: 14px">、致病基因检‹¹‹ç­‰é€”径ã€?/span><span style="font-family: 宋体;font-size: 14px">FFA‹‚€æŸ¥èƒ½å‘现早期æ—?/span><span style="font-family: 宋体;font-size: 14px">症状è€?/span><span style="font-family: 宋体;font-size: 14px">,可明¼‹®ç—…变范围和预示病情发展,指导æ²È–—ã€?/span><span style="font-family: 宋体;font-size: 14px"><span style="font-family:宋体">因此一旦确è¯?/span><span style="font-family:宋体">F</span></span><span style="font-family: 宋体;font-size: 14px">EVR</span><span style="font-family: 宋体;font-size: 14px"><span style="font-family:宋体">åQŒå…¶˜q‘亲属即使没有ä“Q何äÍ床症状也å»ø™®®è¡?/span><span style="font-family:宋体">F</span></span><span style="font-family: 宋体;font-size: 14px">FA</span><span style="font-family: 宋体;font-size: 14px">‹‚€æŸ¥ã€?/span><span style="font-family: 宋体;font-size: 14px">òq¿è§’</span><span style="font-family: 宋体;font-size: 14px">眼底</span><span style="font-family: 宋体;font-size: 14px"><span style="font-family:宋体">照相技术具有无创、快速便æïL­‰ç‰¹ç‚¹</span>, 可应用于FEVR患者的快速筛‹‚€å’Œè¯Šæ–?/span><span style="font-family: 宋体;font-size: 14px">ã€?/span><span style="font-family: 宋体;font-size: 14px">æ‚?/span><span style="font-family: 宋体;font-size: 14px">者病变程度不å?/span><span style="font-family: 宋体;font-size: 14px">,æ²È–—æ–ÒŽ³•å„异,主要包括:视网膜激å…?/span><span style="font-family: 宋体;font-size: 14px">光凝术、å¬m膜外垫压术、玻璃体切割术及æŠ?/span><span style="font-family: 宋体;font-size: 14px">-VEGF药物</span><span style="font-family: 宋体;font-size: 14px">的辅助治疗ã€?/span></p><p style="background: rgb(255, 255, 255)"><span style="font-family: 宋体;font-size: 14px"> </span></p><p style="background: rgb(255, 255, 255); text-align: center;"><img src="/ysguploads/xww/20231106/202311060942218418.png" title="image.png" _src="/ysguploads/xww/20231106/202311060942218418.png" alt="image.png" width="179" height="145" style="width: 179px; height: 145px;"/>   <img src="/ysguploads/xww/20231106/202311060942339500.png" title="image.png" _src="/ysguploads/xww/20231106/202311060942339500.png" alt="image.png"/></p><p style="background: rgb(255, 255, 255); text-align: center;"><span style="font-family: ½{‰çº¿;">造媄          </span><span style="font-family: ½{‰çº¿;">òq¿è§’眼底照相</span></p><p><span style=";font-family:½{‰çº¿;font-size:14px"></span><br/></p><p style="background: rgb(255, 255, 255); text-indent: 2em;"><span style="font-family: 宋体;">怎么预防˜q™ç§ç—…å‘¢åQ?/span><br/><span style="font-family: 宋体;font-size: 14px"></span></p><p style="text-indent: 28px;background: rgb(255, 255, 255)"><span style="font-family: 宋体;font-size: 14px">早期½{›æŸ¥å’Œå¹²é¢„是</span><span style="font-family: 宋体;font-size: 14px">F</span><span style="font-family: 宋体;font-size: 14px">EVR患儿获得良好视功能的关键åQ?/span><span style="font-family: 宋体;font-size: 14px">目前可以使用产前遗传学分析与­‘…声¾l“合以及基因‹‚€‹¹‹ç­‰æŠ€æœ¯ï¼Œå¤§å¤§æé«˜</span><span style="font-family: 宋体;font-size: 14px">FEVR</span><span style="font-family: 宋体;font-size: 14px">的诊出率åQŒé¢„‹¹‹é«˜å±å©´å„¿çš„出生预后。äÍ床工作中˜q˜éœ€åŠ å¼ºå©´å¹¼å„¿çˆ¶æ¯å¯¹æ–°ç”Ÿå„¿çœ¼ç—…的宣教åQŒç¡®ä¿?/span><span style="font-family: 宋体;font-size: 14px">F</span><span style="font-family: 宋体;font-size: 14px">EVR患儿能被</span><span style="font-family: 宋体;font-size: 14px">ž®?/span><span 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